Best DL-Methionine for Cats Tablets, Solutions, and Powders

Besides being one of the protein building blocks, methionine (denoted as Met or M) has many functions in cats including being part of coenzyme S-adenosyl methionine. It will also ensure a healthy coat, skin, heart, eye and so on.

Structurally, it has two isomers, the D and L. The latter is the form that occurs naturally while the former is synthesized. However, both can be utilized by cats, but the D isomer must be converted to L before it can be utilized once it has been absorbed.

Finally, the DL-methionine is a mixture of the two isomers, often done in equal amount for medicinal application.

What is DL-methionine for cats and dogs?

This is an FDA approved prescription medication for some types of urinary stones that may be in be in powder, liquid, capsule, pill or tablet form which may have flavorings added to improve palatability.

DL-methionine for cats - Methio Tabs
Methio Tabs


Its main functions include the following:

  • According to 1800PetMDs, it is a “urinary acidifier used to treat and prevent certain types of urinary stones. It can help prevent urinary tract infections and bladder stones” in cats and dogs.
  • It is used to reduce urine odor in cats and dogs since it reduces the ammonia amounts.
  • It may help protect the kidney because it is a “natural chelating agent for heavy metals, states Petplace.


Brands include DL-Methionine 200mg or 500mg Tablets by Vet Pharmaceutical chewable tablets – Goes for $31.19 for 1000 tablets the 500mg while the 200mg goes for $16.09 at VetRxDirect.

The price for 200mg and 500mg when you are considering the 150 tablets is $5.89 and $8.59 respectively.

Other brands include Ammonil®, Methio-Tabs®, and Methio-Form® all meant for cats and dogs. There are also human formulations.

Possible side effects

Anorexia, diarrhea, nausea, and vomiting are commonly noted side effects. Other side effects may occur. In case of any, let your vet know about them. Also, cats may suffer from Heinz body anemia upon the use of this medication.


You will get them in 200mg, 500mg. You need to give one 500mg tablet for 10-pound weighing cats twice a day, given with food to avoid GI upsets.  This is the same ration for different weights, i.e., if your cat is 5 pounds, give half the amount.

Not that it can be mixed with food especially the liquid and powder form or be available as a chewable tablet.

Your vet may also help you adjust these dosages to ensure urine pH remains below 6.6 since higher pH levels have been associated with some urinary stones.

Overdose and missed dose

In case of a missed dosage, do so as soon as you remember and for any overdose, talk to your vet immediately.

Signs of overdose may include loss of coordination, appetite, and cyanosis where their mucous membrane and skin may turn purple or blue.

When not to use DL-methionine

If your feline friend suffers from pancreatic, liver or kidney disease, do not give them this medication. Also, in case of any allergic reactions, discontinue its use.

Possible interactions

When using gentamicin, amikacin, quinidine or any other aminoglycoside antibiotics, first discuss with your veterinarian before using it.

See also

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